Psychiatry

Adolescent psychiatry markers predict adult psychosis risk.

In a Finnish birth cohort of 27,626 adolescent psychiatry patients, cumulative risk of psychosis by age 30 was 8.5%. Higher number of adolescent diagnoses, parental psychosis, prematurity, young maternal age, inpatient admission, prior child psychiatry contact, and older age at first contact predicted later psychosis. These factors can be used to stratify risk within specialist adolescent clinical populations for targeted monitoring and early intervention. 1

Shelter-based psychiatric program associated with housing attainment.

In a 5-year retrospective cohort of 208 shelter residents receiving on-site psychiatric care, 46.6% attained housing after exit. Each additional year of age increased odds of housing attainment (OR 1.03), while alcohol use disorder (OR 0.54) and opioid/methamphetamine use (OR 0.29) reduced odds. On-site integrated psychiatric, social-welfare, and referral services may bridge shelters to housing, but findings are observational and context-specific. 2

Higher Bipolarity Index links to mood-stabilizer or SGA primary therapy in stable MDD.

Among 103 long-term stable outpatients with MDD, BI scores were higher in the MS/SGA group (mean 24.1) than the antidepressant group (mean 13.3). A BI cutoff of 16 discriminated MS/SGA prescribing with 69.4% sensitivity and 77.8% specificity (AUC 0.765). This cross-sectional association reflects prescribing patterns but does not establish that MS/SGA are superior for BI-defined bipolarity. 3