Preventive Medicine

mHealth education produced small BP and triglyceride improvements in hypertensive adults

In a single‑arm cohort of 408 adults with hypertension, mobile health education was associated with SBP decline from 131 to 128 mmHg over two years. DBP fell from 84 to 82 mmHg and triglycerides decreased from 141 to 127 mg/dL, both statistically significant. LDL changed minimally (127→126 mg/dL) and HDL was unchanged; fasting glucose increased slightly. As an observational, single‑arm study, results support feasibility but not causal inference or substitution for guideline therapies. 1

Community health worker–led education improved precision‑medicine knowledge and care delivery

In a randomized trial of 110 low‑income, racial/ethnic minority oncology patients, adding a 12‑month patient education component run by community health workers increased precision‑medicine knowledge (mean difference 4.17, 95% CI 2.33–7.48; p<0.001). Intervention patients had higher patient activation and satisfaction, fewer ED visits and hospitalizations, and greater receipt of molecular testing and targeted therapy. The trial shows patient‑level education can close delivery gaps in community oncology settings. Consider embedding community health workers for education to improve testing and targeted treatment uptake. 2

ABCS multicomponent intervention reduced 10‑year ASCVD risk in people living with HIV

In a stepped‑wedge trial across nine clinics (485 PLWH aged 40–75, baseline ASCVD risk ≥5%), the ABCS intervention reduced 10‑year ASCVD risk by −0.47 (95% CI −0.93 to −0.01) when analyzed by actual start dates. Cholesterol lowering and smoking cessation drove the benefit, and there was no worsening of HIV viral suppression. COVID‑related startup delays altered assigned start‑date analyses, producing nonsignificant results by intention timing. Implement ABCS‑focused multicomponent programs cautiously, accounting for operational delays and monitoring viral suppression. 3